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Complications of Transcatheter Closure in Patent Ductus Arteriosus Patients

AUTHORS

faranak Behnaz 1 , Azita Chegini 2 , * , Sima Rafieyian 3 , Mahboobe Rasouli 4

AUTHORS INFORMATION

1 Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran

3 Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

How to Cite: Behnaz F, Chegini A, Rafieyian S, Rasouli M . Complications of Transcatheter Closure in Patent Ductus Arteriosus Patients, Int Cardio Res J. 2017 ; 11(4):e11300.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 11 (4); e11300
Published Online: December 01, 2017
Article Type: Research Article
Received: March 04, 2017
Accepted: September 24, 2017

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Abstract

Background: Published studies have shown excellent success rates and also low rates of
life-threatening complications with trans-catheter closure of patent ductus arteriosus
(PDA). However, most studies to date have been conducted in developed nations and
reports from developing countries such as Iran are lacking.
Objectives: To report our experience with trans-catheter closure of patent ductus
arteriosus (PDA) and compare two devices and complications.
Patients and Methods: From 2007 to 2011, 72 consecutive PDA cases were prospectively
enrolled. For PDAs ≤ 2 mm, the coiling method was employed whereas patients with
PDA > 2 mm received Amplatzer duct occlusion (ADO). Success was defined as trivial
residual shunt (< 1 mm) in the echocardiography performed 30 minutes after the
procedure. After the procedure, the patients were admitted to the pediatric cardiology
ward and observed for 72 hours during which the occurrence of major and minor
complications was monitored. Major complications included cardiac arrest, displacement
and/or embolization of the device and patient needing blood transfusion due to severe
hemorrhage. Sampling was based on convenience method and the patients who had
significant pulmonary artery hypertension were excluded from our study. Statistical
analyses were done using SPSS software version 23 (IBM corp., New York, United States).
Continuous variables are presented as mean ± standard deviation. The Mann-Whitney
U test was used to compare the differences between two independent groups. Categorical
variables were depicted as proportions and compared across the intervention groups,
using Chi-square with Fisher’s exact text where appropriate. In all tests, a P value < 0.05
was deemed necessary to reject the null hypothesis.
Results: With the coiling (n = 39) and Amplatzer methods (n = 33), successful closure was
observed totally and recovered with no major complications. Frequent complications were
benign arrhythmia (44.4%), and hemorrhage in 1 (1.4%) of the patients. Complication
rate did not differ between the two techniques (P > 0.05).
Conclusions: Excellent and comparable success rates for both closure techniques were
observed and no major complications were observed.

Keywords

Cardiac Catheterization Adverse Effects Ductus Arteriosus Treatment Outcome Cardiovascular Surgical Procedures

© 0, Shiraz University of Medical Sciences.

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References

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