Heart Function and Remodeling after Successful Balloon Valvuloplasty for Congenital Aortic Stenosis in Children

AUTHORS

Hamid Amoozgar 1 , Hamid Mohammadi 1 , Farid Sharivar 2 , Mohammad Borzoee 1 , Gholamhossein Ajami 1 , Mohammadreza Edraki 1 , Nima Mehdizadegan 1 , Kambiz Keshavarz 3 , *

1 Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2 Shiraz University of Medical Sciences, Shiraz, Iran

3 Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran

How to Cite: Amoozgar H , Mohammadi H, Sharivar F, Borzoee M , Ajami G, et al. Heart Function and Remodeling after Successful Balloon Valvuloplasty for Congenital Aortic Stenosis in Children, Int Cardio Res J. 2018 ; 12(3):e56007.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 12 (3); e56007
Published Online: September 01, 2018
Article Type: Research Article
Received: August 27, 2018
Accepted: May 19, 2018

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Abstract

Background:

 

 

Congenital Aortic Stenosis (AS) is a common problem among congenital heart diseases and balloon valvuloplasty is known as the procedure of choice for treatment.

 

 

Objectives:

 

 

This study aimed at evaluation of the function and remodeling of the heart after a successful balloon AS valvuloplasty.

 

 

Patients and Methods:

 

 

From September 2012 to 2016, 33 patients with congenital AS who had successful balloon valvuloplasty were enrolled into this study. All patients were evaluated by 2D, M-mode, Doppler, and tissue Doppler echocardiography before and after the procedure. The data were analyzed using the SPSS statistical software.

 

 

Results:

 

 

The median duration of follow-up was 2 years (range = 6 months to 7.4 years). Besides, the mean of immediate peak-to-peak gradient reduction was 41.50 ± 17.36 mmHg. Moderate to severe aortic insufficiency occurred in less than 28% of the patients. Additionally, M-mode echocardiography showed residual left ventricular hypertrophy in 50% of the patients. Moreover, E∕A ratio was less than -2 Z-scores in 73% of the patients. E/Ea ratio was also more than 2 Z-scores in 50% of the patients, which was an indicator of diastolic dysfunction. The most common associated lesion was bicuspid aortic valve in 48% of the cases.

 

 

Conclusions:

 

 

Balloon aortic valvuloplasty effectively reduced peak systolic pressure gradient across the aortic valve in patients with congenital AS although left ventricular hypertrophy and diastolic dysfunction persisted in a significant number of patients.

 

 

Keywords

Aortic Valve Stenosis Balloon Valvuloplasty Bicuspid Aortic Bicuspid Aortic Valve

© 0, Shiraz University of Medical Sciences.

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