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Evaluation of Regional Myocardial Systolic Function in the Early Stage of Acute Myocardial Infarction by Strain Rate Imaging

AUTHORS

Maryam Esmaeilzadeh 1 , * , Zahra Alizadeh sani 1 , HR Sanati 1 , M Maleki 1 , H Bakhshandeh Abkenar 1

AUTHORS INFORMATION

1 Department of Echocardiography, Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran

How to Cite: Esmaeilzadeh M, Alizadeh sani Z, Sanati H , Maleki M , Bakhshandeh Abkenar H . Evaluation of Regional Myocardial Systolic Function in the Early Stage of Acute Myocardial Infarction by Strain Rate Imaging, Int Cardio Res J. 2009 ; 3(4):e67867.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 3 (4); e67867
Published Online: December 31, 2009
Article Type: Research Article
Received: February 26, 2018
Accepted: December 31, 2009

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Abstract

Background: We sought to evaluate the impact of different therapeutic strategies on longitudinal regional myocardial
systolic function in the early phase of acute myocardial infarction using strain rate imaging.
Methods: A total of 38 patients (34 males), with first acute myocardial infarction (AMI) were evaluated. Our
patients were divided into 3 groups according to the kind of therapy. The mean age of the patients was 55 ± 9.4
years (range: 39- 75 years). Mean left ventricular ejection fraction (LVEF) in the patients was 41 ± 10.7%. Primary
percutaneous coronary intervention (PCI) was performed in 10 patients. Sixteen patients were treated by
thrombolytic therapy using streptokinase (SK) and 12 were followed-up conservatively. All patients underwent
a comprehensive echocardiography study including SR imaging within 3- 5 days after AMI. The parameters
measured included peak systolic strain (peakε) and strain rate (SRs), end-systolic strain (εes), post systolic shortening
(PSS), time to peak systolic strain rate (tSRs), time to end of shortening (teSRs), post systolic strain (PSε),
post-systolic strain index (PSI), PSS ratio (PSS/ εMax ) and peak postsystolic strain rate (SRPSS).
Results: There was not any association either between WMSI and tå (P=0.4), or MI location and PSS ratio
(P=0.13). But there was an inverse relationship between WMSI and mean SRS, especially when WMSI was
more pronounced. A significant relationship was found between tε and teSRs with the kind of therapy (shorter in
PCI group (P= 0.04). Using a simple linear regression model, no association was found between PSS ratio and
SRs (â=0.056, P =0.70), PSI and teSRs (β= -0.772, P =0.12). Simple linear regression model showed a weak but
significant relationship between PSI and Median tε (β = -0.851, P = 0.04; r =0.33).
Conclusion: Our study showed that PCI resulted in early recovery of regional systolic function of infarcted
myocardium during the early stage of acute myocardial infarction.

Keywords

Regional myocardial systolic function Myocardial infarction Primary PCI Thrombolytic therapy

© 0, Shiraz University of Medical Sciences.

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References

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