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Alcoholic Cardiomyopathy: Clinical and Molecular Findings

AUTHORS

M Correale 1 , * , I Laonigro 2 , F Altomare 2 , MDi Biase 1

1 Department of Cardiology, University of Foggia, Italy

2 Institute of Internal Medicine, Department of Medical and Occupational Sciences University of Foggi, Italy

How to Cite: Correale M , Laonigro I , Altomare F , Biase M . Alcoholic Cardiomyopathy: Clinical and Molecular Findings, Int Cardio Res J. 2009 ; 2(1):e68544.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 2 (1); e68544
Published Online: March 31, 2008
Article Type: Review Article
Received: March 14, 2018
Accepted: March 31, 2008

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Abstract

It has been known for some decades that chronic alcoholism can lead to dilated cardiomyopathy. Although excessive
drinking is known to result in alcoholic cardiomyopathy and light-to-moderate drinking may confer some
cardiovascular benefits, recent studies suggest that it is not only the quantity, but also drinking patterns and genetic
factors, that may influence the relation between alcohol consumption and cardiovascular disease. Alcoholic
patients consuming > 90g of alcohol a day for > 5 years are at risk for the development of asymptomatic alcoholic
cardiomyopathy. Those who continue to drink may become symptomatic and develop signs and symptoms of
heart failure. We summarize the experimental and clinical evidence regarding the role of alcohol in pathophysiology
of alcoholic cardiomyopathy.

Keywords

Alcoholic Cardiomyopathy Heart Failure Congestive Heart Failure

© 0, Shiraz University of Medical Sciences.

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