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Ischemic Preconditioning and Atrial Fibrillation after Coronary Artery Bypass Grafting Surgery

AUTHORS

M Janati 1 , * , Javad Kojuri 1

AUTHORS INFORMATION

1 Cardiovascular Research Center, , Shiraz University of Medical Sciences, Shiraz, Iran

How to Cite: Janati M , Kojuri J . Ischemic Preconditioning and Atrial Fibrillation after Coronary Artery Bypass Grafting Surgery, Int Cardio Res J. 2009 ; 2(1):e68624.

ARTICLE INFORMATION

International Cardiovascular Research Journal: 2 (1); e68624
Published Online: March 31, 2008
Article Type: Research Article
Received: March 14, 2018
Accepted: March 31, 2008

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Abstract

Background: Atrial fibrillation is the most common arrhythmic complication after coronary artery bypass
grafting. Ischemic preconditioning has proved to be a potent endogenous factor in suppressing ischemia- reperfusion
induced arrhythmia.
Patients and Methods: In this prospective study, 101 patients were randomly selected and divided into two
groups including 50 patients with ischemic preconditioning protocol and 51 patients in the control group. Data
were collected from 24 hour electrocardiogram from 1 day before the operation to 3rd post-operative day. Atrial
fibrillation was registered as positive, if it lasted longer than 30 seconds.
Results: The postoperative atrial fibrillation was significantly lower in the ischemic preconditioning group that
was 8% in ischemic preconditioning and 23.52% in control groups (P=0.033). Control group had a longer stay
in intensive care unit and longer mechanical ventilation support.
Conclusion: This study suggests that ischemic preconditioning is a useful prophylactic protocol to decrease the
prevalence of post-cardiac surgery atrial fibrillation.

Keywords

Ischemic Preconditioning Atrial Fibrillation Coronary Artery Bypass Grafting

© 0, Shiraz University of Medical Sciences.

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References

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