The Antihyperlipidemic Effects of Resveratrol in Rats with Simultaneous Type II Diabetes and Renovascular Hypertension

Authors Information
Article Notes and Dates
To Cite : Mozafari M, Nekooeian A A, Panjeshahin M R. The Antihyperlipidemic Effects of Resveratrol in Rats with Simultaneous Type II Diabetes and Renovascular Hypertension, Int Cardio Res J. Online ahead of Print ;10(4):e9804.
Copyright: Copyright © 0, Shiraz University of Medical Sciences. .
Abstract
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Cantos E, Espin JC, Tomas-Barberan FA. Varietal differences among the polyphenol profiles of seven table grape cultivars studied by LC-DAD-MS-MS. J Agric Food Chem. 2002; 50(20): 5691-6[PubMed]
  • 2. Zibaeenezhad MJ, Aslani A, Moniri A, Kheiri MA, Heydari ST, Amanat A, et al. Interventional Revascularization of Coronary Artery Lesions in Diabetic Patients; In-hospital and One Year Follow up. Int Cardiovasc Res J. 2012; 6(4): 113-7[PubMed]
  • 3. Wada M, Kido H, Ohyama K, Ichibangase T, Kishikawa N, Ohba Y, et al. Chemiluminescent screening of quenching effects of natural colorants against reactive oxygen species: evaluation of grape seed, monascus, gardenia and red radish extracts as multi-functional food additives. Food Chem. 2007; 101(3): 980-6
  • 4. Shanmuganayagam D, Warner TF, Krueger CG, Reed JD, Folts JD. Concord grape juice attenuates platelet aggregation, serum cholesterol and development of atheroma in hypercholesterolemic rabbits. Atherosclerosis. 2007; 190(1): 135-42[DOI][PubMed]
  • 5. God JM, Tate P, Larcom LL. Anticancer effects of four varieties of muscadine grape. J Med Food. 2007; 10(1): 54-9[DOI][PubMed]
  • 6. Jung KJ, Wallig MA, Singletary KW. Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Lett. 2006; 233(2): 279-88[DOI][PubMed]
  • 7. Aghasadeghi K, Ahmadi A, Zibaeenezhad MJ, Heydari ST, Abtahi F, Zamirian M, et al. Correlation between fasting blood sugar and resting blood pressure in teachers residing in shiraz, iran 2009. Inter Cardivascular Res J. 2011; 5(1): 14-8
  • 8. Zern TL, Wood RJ, Greene C, West KL, Liu Y, Aggarwal D, et al. Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress. J Nutr. 2005; 135(8): 1911-7[PubMed]
  • 9. Leonard SS, Xia C, Jiang BH, Stinefelt B, Klandorf H, Harris GK, et al. Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun. 2003; 309(4): 1017-26[PubMed]
  • 10. Colivicchi F, Mettimano M, Genovesi-Ebert A, Schinzari F, Iantorno M, Melina G, et al. Differences between diabetic and non-diabetic hypertensive patients with first acute non-ST elevation myocardial infarction and predictors of in-hospital complications. J Cardiovasc Med (Hagerstown). 2008; 9(3): 267-72[DOI][PubMed]
  • 11. Sarikonda KV, Watson RE, Opara OC, Dipette DJ. Experimental animal models of hypertension. J Am Soc Hypertens. 2009; 3(3): 158-65[DOI][PubMed]
  • 12. Cheng J, Zhou W, Warner GM, Knudsen BE, Garovic VD, Gray CE, et al. Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension. Am J Physiol Renal Physiol. 2009; 297(4)-68
  • 13. Movahed A, Nabipour I, Lieben Louis X, Thandapilly SJ, Yu L, Kalantarhormozi M, et al. Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients. Evid Based Complement Alternat Med. 2013; 2013: 851267[DOI][PubMed]
  • 14. Nekooeian AA, Khalili A, Khosravi MB. Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. J Asian Nat Prod Res. 2014; 16(9): 953-62[DOI][PubMed]
  • 15. Midha T, Nath B, Kumari R, Rao YK, Pandey U. WJMA. Meta-Analysis. 2013; : 83
  • 16. Hocher B, Godes M, Olivier J, Weil J, Eschenhagen T, Slowinski T, et al. Inhibition of left ventricular fibrosis by tranilast in rats with renovascular hypertension. J Hypertens. 2002; 20(4): 745-51[PubMed]
  • 17. Al-Suraih M, Grande JP. Management of renal artery stenosis: What does the experimental evidence tell us? World J Cardiol. 2014; 6(8): 855-60[DOI][PubMed]
  • 18. Nekooeian AA, Khalili A, Khosravi MB. Effects of Short-term Renovascular Hypertension and Type 2 Diabetes on Cardiac Functions in Rats. Iran J Med Sci. 2014; 39(1): 51-9[PubMed]
  • 19. Mozafari M, Nekooeian AA, Panjeshahin MR, Zare HR. The effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. Iran J Med Sci. 2015; 40(2): 152-60[PubMed]
  • 20. Nekooeian AA, Mashhoodi T. Solid plexiglass clips to induce reproducible renal hypertension in the rat. Iran J Pharmacol. 2007; 39(1): 25
  • 21. Janahmadi Z, Nekooeian AA, Mozafari M. Hydroalcoholic extract of Allium eriophyllum leaves attenuates cardiac impairment in rats with simultaneous type 2 diabetes and renal hypertension. Res Pharm Sci. 2015; 10(2): 125-33[PubMed]
  • 22. Nekooeian AA, Khalili A, Khosravi MB. Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension. Indian J Pharmacol. 2014; 46(4): 398-403[DOI][PubMed]
  • 23. Nekooeian AA, Eftekhari MH, Adibi S, Rajaeifard A. Effects of pomegranate seed oil on insulin release in rats with type 2 diabetes. Iran J Med Sci. 2014; 39(2): 130-5[PubMed]
  • 24. Lerman LO, Nath KA, Rodriguez-Porcel M, Krier JD, Schwartz RS, Napoli C, et al. Increased oxidative stress in experimental renovascular hypertension. Hypertension. 2001; 37(2 Pt 2): 541-6[PubMed]
  • 25. de Simone G, Devereux RB, Camargo MJ, Wallerson DC, Laragh JH. Influence of sodium intake on in vivo left ventricular anatomy in experimental renovascular hypertension. Am J Physiol. 1993; 264(6 Pt 2)-10[PubMed]
  • 26. Arata M, de Bruno LF, Volpini WMG, Quintans JC, D'alessandro VG, Braun M, et al. β-cell function in mice injected with mononuclear splenocytes from multiple-dose streptozotocin diabetic mice. Experiment Biol Med. 1994; 206(1): 76-82
  • 27. Reddy S, Wu D, Elliott RB. Low dose streptozotocin causes diabetes in severe combined immunodeficient (SCID) mice without immune cell infiltration of the pancreatic islets. Autoimmunity. 1995; 20(2): 83-92[PubMed]
  • 28. Rees DA, Alcolado JC. Animal models of diabetes mellitus. Diabet Med. 2005; 22(4): 359-70[DOI][PubMed]
  • 29. Wiesel P, Mazzolai L, Nussberger J, Pedrazzini T. Two-kidney, one clip and one-kidney, one clip hypertension in mice. Hypertension. 1997; 29(4): 1025-30[PubMed]
  • 30. Esteghamati A, Meysamie A, Khalilzadeh O, Rashidi A, Haghazali M, Asgari F, et al. Third national Surveillance of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) in Iran: methods and results on prevalence of diabetes, hypertension, obesity, central obesity, and dyslipidemia. BMC Public Health. 2009; 9: 167[DOI][PubMed]
  • 31. Zahner D, Malaisse WJ. Kinetic behaviour of liver glucokinase in diabetes. I. Alteration in streptozotocin-diabetic rats. Diabetes Res. 1990; 14(3): 101-8[PubMed]
  • 32. Khalili A, Nekooeian AA, Khosravi MB, Fakher S. Simultaneous renal hypertension and type 2 diabetes exacerbate vascular endothelial dysfunction in rats. Int J Exp Pathol. 2012; 93(3): 210-7[DOI][PubMed]
  • 33. Bolzan AD, Bianchi MS. Genotoxicity of streptozotocin. Mutat Res Rev Mutat Res. 2002; 512(2): 121-34
  • 34. Hattori R, Otani H, Maulik N, Das DK. Pharmacological preconditioning with resveratrol: role of nitric oxide. Am J Physiol Heart Circ Physiol. 2002; 282(6)-95[DOI][PubMed]
  • 35. Palsamy P, Subramanian S. Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. J Cell Physiol. 2010; 224(2): 423-32[DOI][PubMed]
  • 36. Friedman J, Peleg E, Kagan T, Shnizer S, Rosenthal T. Oxidative stress in hypertensive,diabetic, and diabetic hypertensive rats. Am J Hypertens. 2003; 16(12): 1049-52[PubMed]
  • 37. Hung LM, Su MJ, Chen JK. Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms. Free Radic Biol Med. 2004; 36(6): 774-81[DOI][PubMed]
  • 38. Factor SM, Bhan R, Minase T, Wolinsky H, Sonnenblick EH. Hypertensive-diabetic cardiomyopathy in the rat: an experimental model of human disease. Am J Pathol. 1981; 102(2): 219-28[PubMed]
  • 39. Pieske B, Wachter R. Impact of diabetes and hypertension on the heart. Curr Opin Cardiol. 2008; 23(4): 340-9[DOI][PubMed]
  • 40. Su HC, Hung LM, Chen JK. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats. Am J Physiol Endocrinol Metab. 2006; 290(6)-46[DOI][PubMed]
  • 41. Szkudelski T, Szkudelska K. Anti-diabetic effects of resveratrol. Ann N Y Acad Sci. 2011; 1215: 34-9[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiaion Alert via Google Reader

Cited By:

International Cardiovascular Research Journal accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check